A genome-scale screen for synthetic drivers of T cell proliferation
Mateusz Legut, Zoran Gajic, Maria Guarino, Zharko Daniloski, Jahan Rahman, Xinhe Xue, Congyi Lu, Lu Lu, Eleni P. Mimitou, Stephanie Hao, Teresa Davoli, Catherine Diefenbach, Peter Smibert, Neville E. Sanjana
Topics & Concepts
Chimeric antigen receptorBiologyT cellCD8Cell biologyAntigenComputational biologyCancer researchImmunologyImmune systemCAR-T cell therapy researchCRISPR and Genetic EngineeringSingle-cell and spatial transcriptomics