Spinosin inhibits activated hepatic stellate cell to attenuate liver fibrosis by targeting Nur77/ASK1/p38 MAPK signaling pathway
Gang Lin, Weibin Li, Wenbin Hong, Zhu Desheng, Hongyu Hu, Jiqiang Fu, Yanfang Gao, Shuaijie Chen, Dajun Chai, Jin-Zhang Zeng
Topics & Concepts
Nerve growth factor IBHepatic stellate cellHepatoprotectionFibrosisHepatic fibrosisMAPK/ERK pathwayCancer researchPharmacologyBiologySignal transductionCell biologyChemistryNuclear receptorBiochemistryMedicineEndocrinologyTranscription factorInternal medicineGlutathioneEnzymeGeneNuclear Receptors and SignalingLiver physiology and pathologySignaling Pathways in Disease