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<i>Enterococcus faecalis</i> shifts macrophage polarization toward M1-like phenotype with an altered cytokine profile

Mohamed Mohamed Elashiry, Fucong Tian, Mahmoud Elashiry, Rana Zeitoun, Ranya Elsayed, Matthew L. Andrews, Brian E. Bergeon, Christopher W. Cutler, Franklin R. Tay

2021Journal of Oral Microbiology27 citationsDOIOpen Access PDF

Abstract

infection of bone marrow-derived stem cells during differentiation into macrophages induces an atypical M1-like phenotype associated with intracellular bacterial survival.

Topics & Concepts

Macrophage polarizationCytokineMacrophageBiologyM2 MacrophageEnterococcus faecalisImmunologyPhenotypeMicrobiologyInnate immune systemCD38Immune systemCell biologyStem cellIn vitroStaphylococcus aureusGeneBiochemistryBacteriaCD34GeneticsImmune Response and InflammationImmune cells in cancerCancer Research and Treatments
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