Updating the CSIC Reaction (2003–2020)
Alexey V. Dobrydnev, José Marco‐Contelles
Abstract
Abstract Herein, we have updated the progress and developments of the Carbanion‐mediated Sulfonate (or Sulfonamide) Intermolecular Coupling, and Intramolecular Cyclization , abbreviated as CSIC reaction (CSICr), in the last seventeen years from the seminal review published in 2003 in this same Journal . CSICr has proven to be a useful and versatile synthetic tool, efficiently providing a number of open‐chain [alkane(sulfonamide)sulfonates] or cylic (sultams and sultones) synthetic intermediates or final products of high value in organic and medicinal chemistry.
Topics & Concepts
ChemistryCarbanionSulfonamideSulfonateIntramolecular forceCombinatorial chemistryOrganic chemistrySodiumOrganic and Inorganic Chemical ReactionsChemical synthesis and alkaloidsSulfur-Based Synthesis Techniques