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Geroscience in the Age of COVID-19

Nir Barzilai, James Appleby, Steven N. Austad, Ana María Cuervo, Matt Kaeberlein, Christian González‐Billault, Stephanie Lederman, Ilia Stambler, Felipe Sierra

2020Aging and Disease30 citationsDOIOpen Access PDF

Abstract

The data on COVID-19 is clear on at least one point: Older adults are most vulnerable to hospitalization, disability and death following infection with the novel coronavirus. Therefore, therapeutically addressing degenerative aging processes as the main risk factors appears promising for tackling the present crisis and is expected to be relevant when tackling future infections, epidemics and pandemics. Therefore, utilizing a geroscience approach, targeting aging processes to prevent multimorbidity, via initiating broad clinical trials of potential geroprotective therapies, is recommended.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)PandemicMedicine2019-20 coronavirus outbreakSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Intensive care medicineClinical trialCoronavirusOutbreakDiseaseVirologyPathologyInfectious disease (medical specialty)Genetics, Aging, and Longevity in Model OrganismsDietary Effects on HealthFrailty in Older Adults
Geroscience in the Age of COVID-19 | Litcius