Design, synthesis and biological evaluation of a new series of imidazothiazole-hydrazone hybrids as dual EGFR and Akt inhibitors for NSCLC therapy
Mehlika Dilek Altıntop, İpek Ertorun, Gülşen Akalın Çiftçi, Ahmet Özdemır
Topics & Concepts
ChemistryHydrazoneDual (grammatical number)Protein kinase BSeries (stratigraphy)HybridPharmacologyStereochemistryPhosphorylationBiochemistryBotanyBiologyLiteraturePaleontologyArtLung Cancer Treatments and MutationsCytokine Signaling Pathways and InteractionsSynthesis and biological activity