Recent Advances in Visible Light-Induced C-H Functionalization of Imidazo[1,2-a]pyridines
Juanjuan Gao, Xinlei Fu, Kai Yang, Zhaowen Liu
Abstract
The imidazo[1,2-a]pyridine skeleton is widely present in many natural products and pharmaceutical agents. Due to its impressive and significant biological activities, such as analgesic, anti-tumor, antiosteoporosis, and anxiolytic properties, the derivatization of imidazo[1,2-a]pyridine skeleton has attracted widespread attention from chemists. In recent years, significant progress has been made in the derivatization of imidazo[1,2-a]pyridines through direct C-H functionalization, especially through visible light induction. This review highlights recent advances in visible light-induced C-H functionalization of imidazo[1,2-a]pyridines during the past ten years, and some reaction mechanisms are also discussed.