Litcius/Paper detail

Synthesis and biological evaluation of 3-styrylchromone derivatives as selective monoamine oxidase B inhibitors

Koichi Takao, Yuri Takemura, Junko Nagai, Hitoshi Kamauchi, Kaori Hoshi, Ryo Mabashi, Yoshihiro Uesawa, Yoshiaki Sugita

2021Bioorganic & Medicinal Chemistry18 citationsDOIOpen Access PDF

Topics & Concepts

ChemistryMonoamine oxidaseMonoamine oxidase BQuantitative structure–activity relationshipStereochemistrySelectivityIC50Structure–activity relationshipRing (chemistry)Monoamine oxidase AChromoneEnzymeBiochemistryIn vitroOrganic chemistryCatalysisSynthesis of Organic CompoundsOxidative Organic Chemistry ReactionsChemical synthesis and alkaloids