Application of hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry for the retention and sensitivity studies of antisense oligonucleotides
Anna Kilanowska, Bogusław Buszewski, Sylwia Studzińska
Topics & Concepts
ChemistryChromatographyOligonucleotideHydrophilic interaction chromatographyMass spectrometrySelectivityTandem mass spectrometryLiquid chromatography–mass spectrometryHigh-performance liquid chromatographyDNAOrganic chemistryCatalysisBiochemistryAnalytical Chemistry and ChromatographyMicrofluidic and Capillary Electrophoresis ApplicationsProtein purification and stability