Litcius/Paper detail

FDI-6 and olaparib synergistically inhibit the growth of pancreatic cancer by repressing BUB1, BRCA1 and CDC25A signaling pathways

Shiqi Wu, Shihui Huang, Qianwen Lin, Yixuan Tang, Lei Huang, Yungen Xu, Shuping Wang

2021Pharmacological Research20 citationsDOI

Topics & Concepts

OlaparibPARP1Cancer researchDNA damagePARP inhibitorFOXM1Cell cycleDNA repairRAD51Synthetic lethalityPancreatic cancerCell biologyBiologyPoly ADP ribose polymeraseCancerGeneticsDNAPolymerasePARP inhibition in cancer therapyFOXO transcription factor regulationDNA Repair Mechanisms
FDI-6 and olaparib synergistically inhibit the growth of pancreatic cancer by repressing BUB1, BRCA1 and CDC25A signaling pathways | Litcius