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Inhibition of SRSF9 enhances the sensitivity of colorectal cancer to erastin-induced ferroptosis by reducing glutathione peroxidase 4 expression

Rui Wang, Qi Su, Hongzhuan Yin, Di Wu, Chi Lv, Zhaopeng Yan

2021The International Journal of Biochemistry & Cell Biology46 citationsDOI

Topics & Concepts

GPX4TransfectionProgrammed cell deathCancer cellSmall hairpin RNACancer researchCarcinogenesisColorectal cancerCellCell biologyChemistryCell cultureCancerBiologyGlutathioneGlutathione peroxidaseApoptosisBiochemistryEnzymeGene knockdownGeneticsFerroptosis and cancer prognosisCancer-related molecular mechanisms researchRNA modifications and cancer
Inhibition of SRSF9 enhances the sensitivity of colorectal cancer to erastin-induced ferroptosis by reducing glutathione peroxidase 4 expression | Litcius