Litcius/Paper detail

Association between Timing of Colonization and Risk of Developing Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae Infection in Hospitalized Patients

Ángela Cano, Belén Gutiérrez‐Gutiérrez, Isabel Machuca, Julián Torre-Giménez, Irene Gracia-Ahufinger, Alejandra M. Natera, Elena Pérez‐Nadales, Juan José Castón, Jesús Rodríguez‐Baño, Luis Martı́nez-Martı́nez, Julián Torre‐Cisneros

2022Microbiology Spectrum25 citationsDOIOpen Access PDF

Abstract

In this study, it was confirmed that patients who became colonized during hospitalization had a higher risk of developing KPC-Kp infection than hospitalized patients who were already colonized at the start of follow-up. Besides, the risk of infection in the group of patients who became colonized during follow-up was greater in the first weeks immediately after colonization was confirmed. Our findings support the need for designing preventive strategies for patients at the highest risk of infection development, including those admitted in high-risk hospital wards and those undergoing urological procedures.

Topics & Concepts

ColonizationKlebsiella pneumoniaeInternal medicineLogistic regressionMedicineCohort studyCohortProspective cohort studyBiologyMicrobiologyBiochemistryEscherichia coliGeneAntibiotic Resistance in BacteriaUrinary Tract Infections ManagementAntibiotic Use and Resistance