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Brønsted Acid Ionic Liquid-Catalyzed Ring Opening of 3,3-Disubstituted Oxetanes in Water: Efficient Access to Furans and Benzofurans

Chunjie Ni, Yining Zhao, Jin‐Ming Yang

2020ACS Sustainable Chemistry & Engineering15 citationsDOI

Abstract

By using water as a solvent, an eco-friendly and practical protocol for the synthesis of furans and benzofurans through a Brønsted acid ionic liquid-catalyzed ring opening of 3,3-disubstituted oxetanes has been disclosed under mild conditions. This process shows broad substrate scope with good to excellent yields. More importantly, the BAIL catalyst can be easily recovered by simple separation and reused six times without significant loss of catalytic activity.

Topics & Concepts

Ionic liquidCatalysisRing (chemistry)ChemistrySolventSubstrate (aquarium)Organic chemistryCombinatorial chemistryGeologyOceanographyIonic liquids properties and applicationsSulfur-Based Synthesis TechniquesOxidative Organic Chemistry Reactions
Brønsted Acid Ionic Liquid-Catalyzed Ring Opening of 3,3-Disubstituted Oxetanes in Water: Efficient Access to Furans and Benzofurans | Litcius