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Maternal heterozygous mutation in CHEK1 leads to mitotic arrest in human zygotes

Beili Chen, Jianying Guo, Ting Wang, Qianhui Lee, Ming Jia, Fangfang Ding, Haitao Li, Zhiguo Zhang, Lin Li, Yunxia Cao, Jie Na

2021Protein & Cell32 citationsDOIOpen Access PDF

Topics & Concepts

ZygoteHuman geneticsMitosisBiologyMutationGeneticsDevelopmental biologyCell biologyEmbryoGeneEmbryogenesisMicrotubule and mitosis dynamicsCancer-related Molecular PathwaysBRCA gene mutations in cancer
Maternal heterozygous mutation in CHEK1 leads to mitotic arrest in human zygotes | Litcius