A new method to amplify colorimetric signals of paper-based nanobiosensors for simple and sensitive pancreatic cancer biomarker detection
K. Sudhakara Prasad, Yousef Abugalyon, Chunqiang Li, Feng Xu, Xiujun Li
Abstract
A low-cost, sensitive, and disposable paper-based immunosensor for instrument-free colorimetric detection of pancreatic cancer biomarker PEAK1 was reported for the first time by capitalizing the catalytic properties of gold nanoparticles in colour dye degradation. This simple signal amplification method enhances the detection sensitivity by about 10 fold.
Topics & Concepts
Pancreatic cancerBiomarkerColloidal goldColorimetryNanotechnologyChemistryComputer scienceCancerNanoparticleMaterials scienceChromatographyMedicineBiochemistryInternal medicineBiosensors and Analytical DetectionAdvanced biosensing and bioanalysis techniquesAdvanced Nanomaterials in Catalysis