Facile synthesis of sulfinate esters from aryl iodides <i>via</i> direct oxidation of thioesters
Keisuke Nakamura, Yukiko Kumagai, Akihiro Kobayashi, Minori Suzuki, Suguru Yoshida
Abstract
A practical method to synthesize sulfinate esters from aryl iodides is disclosed. Direct oxidation of thioesters prepared by copper-catalyzed C-S formation of aryl iodides realized the efficient synthesis of sulfinate esters. Due to the good accessibility of aryl iodides, a wide variety of sulfinate esters were prepared from easily available starting materials such as carboxylic acids and anilines.
Topics & Concepts
ChemistryArylOrganic chemistryCombinatorial chemistryCopperAlkylSulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsCatalytic C–H Functionalization Methods