Genetic and pharmacological targeting of XBP1 alleviates hepatic ischemia reperfusion injury by enhancing FoxO1-dependent mitophagy
Baicheng Kuang, Mengqin Wang, Hao Yan, Qin Jiang, Zhiheng Wang, Haiqiang Ni, Shuaiheng Hou, Xuan Mao Peng, Shiqi Gu, Yuanyuan Zhao, Tongwen Ou, Nianqiao Gong
Topics & Concepts
MitophagyXBP1Reperfusion injuryLiver injuryMitochondrionAutophagyUnfolded protein responseCell biologyEndoplasmic reticulumBiologyPharmacologyChemistryMedicineIschemiaInternal medicineApoptosisBiochemistryRNAGeneRNA splicingAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and DiseaseHeme Oxygenase-1 and Carbon Monoxide