Bexarotene inhibits cell proliferation by inducing oxidative stress, DNA damage and apoptosis via PPARγ/ NF-κB signaling pathway in C6 glioma cells
Ceyhan Hacıoğlu, Fatih Kar, Sedat Kaçar, Varol Şahıntürk, Güngör Kanbak
Topics & Concepts
BexaroteneApoptosisOxidative stressRetinoid X receptorCancer researchBiologyCytotoxic T cellReactive oxygen speciesAnnexinPeroxisome proliferator-activated receptorGliomaCaspase 3ChemistryPharmacologyReceptorNuclear receptorCell biologyProgrammed cell deathEndocrinologyBiochemistryTranscription factorIn vitroGeneRetinoids in leukemia and cellular processesPeroxisome Proliferator-Activated ReceptorsNF-κB Signaling Pathways