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Bexarotene inhibits cell proliferation by inducing oxidative stress, DNA damage and apoptosis via PPARγ/ NF-κB signaling pathway in C6 glioma cells

Ceyhan Hacıoğlu, Fatih Kar, Sedat Kaçar, Varol Şahıntürk, Güngör Kanbak

2021Medical Oncology43 citationsDOIOpen Access PDF

Topics & Concepts

BexaroteneApoptosisOxidative stressRetinoid X receptorCancer researchBiologyCytotoxic T cellReactive oxygen speciesAnnexinPeroxisome proliferator-activated receptorGliomaCaspase 3ChemistryPharmacologyReceptorNuclear receptorCell biologyProgrammed cell deathEndocrinologyBiochemistryTranscription factorIn vitroGeneRetinoids in leukemia and cellular processesPeroxisome Proliferator-Activated ReceptorsNF-κB Signaling Pathways
Bexarotene inhibits cell proliferation by inducing oxidative stress, DNA damage and apoptosis via PPARγ/ NF-κB signaling pathway in C6 glioma cells | Litcius