Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity
Junyun Lai, Sherly Mardiana, Imran G. House, Kevin Sek, Melissa A. Henderson, Lauren Giuffrida, Amanda X. Y. Chen, Kirsten L. Todd, Emma V. Petley, Jack D. Chan, Emma M. Carrington, Andrew M. Lew, Benjamin Solomon, Joseph A. Trapani, Katherine Kedzierska, Maximilien Evrard, Stephin J. Vervoort, Jason Waithman, Phillip K. Darcy, Paul A. Beavis
Topics & Concepts
EpitopeImmunityCell biologyAdoptive cell transferImmunologyDendritic cellImmune systemT cellBiologyAntigenCAR-T cell therapy researchVirus-based gene therapy researchImmunotherapy and Immune Responses