Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332
Yao Zhao, Chao Fang, Qi Zhang, Ruxue Zhang, Xiangbo Zhao, Yinkai Duan, Haofeng Wang, Yan Zhu, Lu Feng, Jinyi Zhao, Maolin Shao, Xiuna Yang, Leike Zhang, Chao Peng, Kailin Yang, Dawei Ma, Zihe Rao, Haitao Yang
Topics & Concepts
ProteaseSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Protease inhibitor (pharmacology)2019-20 coronavirus outbreakVirologyCoronavirus disease 2019 (COVID-19)BiologyEnzymeMedicineBiochemistryHuman immunodeficiency virus (HIV)Viral loadInfectious disease (medical specialty)PathologyAntiretroviral therapyOutbreakDiseaseComputational Drug Discovery MethodsSARS-CoV-2 and COVID-19 ResearchPharmacological Effects of Natural Compounds