Litcius/Paper detail

Selective degradation of BRD4 suppresses lung cancer cell proliferation using GSH-responsive PROTAC precursors

Heli Fan, Zhili Zhou, Dehao Yu, Jing Sun, Luo Wang, Yuanyuan Jia, Junyu Tian, Wenyi Mi, Huabing Sun, Huabing Sun

2023Bioorganic Chemistry35 citationsDOI

Topics & Concepts

ChemistryGlutathioneCancer cellProteasomeCancerCancer researchProtein degradationProteolysisLung cancerCell growthBRD4Cell biologyIntracellularEpigeneticsPharmacologyBiochemistryBiologyMedicineInternal medicineBromodomainEnzymeGeneProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysMultiple Myeloma Research and Treatments
Selective degradation of BRD4 suppresses lung cancer cell proliferation using GSH-responsive PROTAC precursors | Litcius