Litcius/Paper detail

[Comparison of four scoring systems for predicting ICU mortality in patients with sepsis].

Chang Hu, Bo Hu, Zhifeng Li, Xiao Yang, Huimin Song, Jianguo Li

2020PubMed19 citationsDOIOpen Access PDF

Abstract

OBJECTIVE: To evaluate the value of Sequential Organ Failure Assessment (SOFA), Simplified Acute Physiology Score Ⅱ (SAPS-Ⅱ), Oxford Acute Severity of Illness Score (OASIS) and Logistic Organ Dysfunction System (LODS) scoring systems for predicting ICU mortality in patients with sepsis. METHODS: We collected the data of a total of 2470 cases of sepsis recorded in the MIMIC-III database from 2001 to 2012 and retrieved the scores of SOFA, SAPS-Ⅱ, OASIS and LODS of the patients within the first day of ICU admission. We compared with the score between the survivors and the non-survivors and analyzed the differences in the area under the ROC curve (AUC) of the 4 scoring systems. Binomial logistic regression was performed to compare the predictive value of the 4 scoring systems for ICU mortality of the patients. RESULTS: =0.350), respectively. CONCLUSIONS: The scores of SOFA, SAPS-Ⅱ, OASIS, and LODS can predict ICU mortality in patients with sepsis, but SAPS-Ⅱ and OASIS scores have better predictive value than SOFA and LODS scores.

Topics & Concepts

SOFA scoreMedicineSepsisSAPS IILogistic regressionInternal medicineReceiver operating characteristicArea under the curveScoring systemAPACHE IIIntensive care unitSepsis Diagnosis and TreatmentInflammation biomarkers and pathwaysHemodynamic Monitoring and Therapy