Cysteine-Based Protein Covalent Binding and Hepatotoxicity Induced by Emodin
Xu Wang, Zifang Ding, Kaiqi Ma, Changhai Sun, Xiaojiao Zheng, Yutong You, Shiyu Zhang, Ying Peng, Jiang Zheng
Abstract
-acetyl cysteine. A good association of protein modification with hepatotoxicity induced by EMD was illustrated, which facilitates the understanding of the mechanism of hepatotoxicity induced by EMD.
Topics & Concepts
CysteineEmodinChemistryPharmacologyGlutathioneButhionine sulfoximineBiochemistryEnzymeMedicinePhytochemistry and biological activity of medicinal plantsPharmacological Effects of Natural CompoundsDrug-Induced Hepatotoxicity and Protection