Decatungstate-photocatalyzed tandem acylation/cyclization/self-hydrogenation of isocyanides with aldehydes to hydroxyalkylated N-heteroarenes <i>via</i> multiple hydrogen atom transfer
Hong‐Tao Ji, Qiong-Hui Peng, Jiasheng Wang, Yuhan Lu, Hui Dai, Qing-Xia Luo, Wei‐Min He
Abstract
A 100% atom economical construction of hydroxyalkylated N-heteroarenes through decatungstate-catalyzed tandem cyclization/self-hydrogenation of isocyanides and aldehydes under exogenous hydrogen reagent- and byproduct-free conditions was developed.
Topics & Concepts
TandemChemistryAcylationHydrogen atomPhotochemistryAtom (system on chip)HydrogenMedicinal chemistryCombinatorial chemistryOrganic chemistryCatalysisGroup (periodic table)Materials scienceComposite materialComputer scienceEmbedded systemRadical Photochemical ReactionsCatalytic C–H Functionalization MethodsSulfur-Based Synthesis Techniques