Culture Variabilities of Human iPSC-Derived Cerebral Organoids Are a Major Issue for the Modelling of Phenotypes Observed in Alzheimer’s Disease
Damián Hernández, Louise Rooney, Maciej Daniszewski, Lerna Gulluyan, Helena H. Liang, Anthony L. Cook, Alex W. Hewitt, Alice Pébay
Topics & Concepts
OrganoidInduced pluripotent stem cellApolipoprotein EBiologyCell cultureHuman brainAlzheimer's diseaseCell biologyCellular differentiationNeurosciencePathologyGeneticsDiseaseMedicineGeneEmbryonic stem cellPluripotent Stem Cells ResearchCRISPR and Genetic EngineeringGenetics, Aging, and Longevity in Model Organisms