Inhibition of MEK-ERK signaling reduces seizures in two mouse models of tuberous sclerosis complex
Lena H. Nguyen, Steven C. Leiser, Dekun Song, Daniela Brunner, Steven L. Roberds, Michael Wong, Angélique Bordey
Topics & Concepts
Tuberous sclerosisMAPK/ERK pathwayMEK inhibitorEpilepsyPI3K/AKT/mTOR pathwayEverolimusMedicineNeuroscienceEpileptogenesisCancer researchPharmacologySignal transductionPsychologyInternal medicineBiologyCell biologyPathologyTuberous Sclerosis Complex ResearchPolyomavirus and related diseases