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Nuclear speckles regulate functional programs in cancer

Katherine A. Alexander, Ruofan Yu, Nicolas Skuli, Nathan J. Coffey, Son C. Nguyen, Christine Faunce, Hua Huang, Ian Dardani, Austin L. Good, Joan Lim, Catherine Y. Li, Nicholas Biddle, Eric F. Joyce, Arjun Raj, Daniel J. Lee, Brian Keith, M. Celeste Simon, Shelley L. Berger

2025Nature Cell Biology17 citationsDOIOpen Access PDF

Topics & Concepts

Speckle patternBiologyGene expressionGeneTranscription factorRegulation of gene expressionCancer researchComputational biologyCell biologyGeneticsComputer scienceArtificial intelligenceRNA Research and SplicingRNA modifications and cancerCancer, Hypoxia, and Metabolism
Nuclear speckles regulate functional programs in cancer | Litcius