Confronting the controversy: interleukin-6 and the COVID-19 cytokine storm syndrome
Luke Y. C. Chen, Ryan L. Hoiland, Sophie Stukas, Cheryl L. Wellington, Mypinder S. Sekhon
Abstract
<b>Hypercytokinaemic immune dysregulation in COVID-19 is known as cytokine storm syndrome. Interleukin-6 levels ≥80 pg·mL<sup>−1</sup> predict an increased risk of respiratory failure and death, and immunomodulatory therapy is an area of urgent investigation.</b>https://bit.ly/3jq3uJ4
Topics & Concepts
Cytokine stormCoronavirus disease 2019 (COVID-19)StormCytokineImmune systemCytokine release syndromeImmunologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)InterleukinMedicineInterleukin 62019-20 coronavirus outbreakVirologyImmunotherapyInternal medicineDiseaseGeographyMeteorologyChimeric antigen receptorOutbreakInfectious disease (medical specialty)COVID-19 Clinical Research StudiesInflammasome and immune disordersImmune Cell Function and Interaction