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Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress and TLR4/NF-kB/NLRP3 pathways

Shaimaa S. Ibrahim, Omar G. Abo Elseoud, Mohamed H. Mohamedy, Mohamed M. Amer, Youssef Y. Mohamed, Shehab A. Elmansy, Mohamed M. Kadry, Ahmed Attia, Ragy A. Fanous, Mahmoud S. Kamel, Youssef A. Solyman, Mazen S. Shehata, Mina Y. George

2021Neuropharmacology86 citationsDOI

Topics & Concepts

Oxidative stressChrysinDoxorubicinChemistryTLR4Cognitive impairmentPharmacologyMedicineNeuroscienceCognitionPsychologyImmunologyInternal medicineBiochemistryInflammationAntioxidantChemotherapyFlavonoidCalcium signaling and nucleotide metabolismCancer-related cognitive impairment studiesNanoplatforms for cancer theranostics
Nose-to-brain delivery of chrysin transfersomal and composite vesicles in doxorubicin-induced cognitive impairment in rats: Insights on formulation, oxidative stress and TLR4/NF-kB/NLRP3 pathways | Litcius