<i>N</i>-Carbamylglutamate and <scp>l</scp>-arginine supplementation improve hepatic antioxidant status in intrauterine growth-retarded suckling lambs
Hao Zhang, Yaqian Jin, Mengzhi Wang, Juan J. Loor, Hongrong Wang
Abstract
< 0.05). Both Arg and NCG can protect neonates from IUGR-induced hepatic oxidative damage through promoting the expression of antioxidative enzymes (including SOD, CAT, and GSH-Px), phase II metabolizing enzymes, and activation of the NO pathway.
Topics & Concepts
Internal medicineMalondialdehydeEndocrinologyGlutathione peroxidaseSuperoxide dismutaseAntioxidantSOD2Oxidative stressGlutathioneNitric oxide synthaseHeme oxygenaseCatalaseArginineChemistryNitric oxideBiologyEnzymeBiochemistryMedicineHemeAmino acidBirth, Development, and HealthFatty Acid Research and HealthInfant Nutrition and Health