Caenorhabditis elegans as a model system for studying aging-associated neurodegenerative diseases
Kate M. Van Pelt, Matthias C. Truttmann
Abstract
neurodegenerative disease models of varying prevalence to emphasize shared mechanisms of proteotoxicity, and highlight the utility of these models in elucidating the molecular basis of ND pathologies.
Topics & Concepts
ProteostasisCaenorhabditis elegansBiologyNeuroscienceNeurodegenerationComputational biologyDiseaseMedicineCell biologyGeneticsPathologyGeneGenetics, Aging, and Longevity in Model OrganismsBiochemical Acid Research StudiesPrion Diseases and Protein Misfolding