Highly-selective detection of EGFR mutation gene in lung cancer based on surface enhanced Raman spectroscopy and asymmetric PCR
Ting Guo, Weimiao Li, Qian Lü, Xiaolong Yan, Daxiang Cui, Jinbo Zhao, Haibin Ni, Xiangwei Zhao, Zhipei Zhang, Xiaofei Li, Lijun Huang, Lei Wang
Topics & Concepts
ChemistryDetection limitNanoclustersDNASurface-enhanced Raman spectroscopyMolecular biologyPolymerase chain reactionMutationRaman spectroscopyRaman scatteringGeneAnalytical Chemistry (journal)ChromatographyBiologyBiochemistryOpticsPhysicsOrganic chemistryAdvanced biosensing and bioanalysis techniquesMolecular Biology Techniques and ApplicationsCancer Genomics and Diagnostics