Chronic exposure of alcohol triggers microglia-mediated synaptic elimination inducing cognitive impairment
Lihuan Lan, Hongxuan Wang, Xiaoni Zhang, Qingyu Shen, Xiangpen Li, Lei He, Xiaoming Rong, Jialing Peng, Jingjing Mo, Ying Peng
Topics & Concepts
NeuroscienceMicrogliaSynapseLong-term potentiationSynaptic plasticitySynaptic pruningDendritic spinePostsynaptic potentialNeurodegenerationTREM2BiologyHippocampusMedicineHippocampal formationReceptorInternal medicineImmunologyInflammationDiseaseNeuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms