Design, synthesis, antibacterial activity evaluation and molecular modeling studies of new sulfonamides containing a sulfathiazole moiety
Tuğba Meşeli, Şengül Dilem Doğan, Miyase Gözde Gündüz, Zülbiye Kökbudak, Sanja Škaro Bogojević, Theresa Noonan, Sandra Vojnović, Gerhard Wolber, Jasmina Nikodinović‐Runić
Abstract
Molecular modifications on sulfathiazole to overcome sulfonamide resistance: the discovery of selective antibacterial agents against <italic>Staphylococcus aureus</italic>.
Topics & Concepts
SulfathiazoleChemistryMoietySulfonamideAntibacterial activityCombinatorial chemistryStaphylococcus aureusSulfisoxazoleStereochemistryAntibioticsOrganic chemistryBacteriaBiochemistryTetracyclineGeneticsBiologyPhenothiazines and Benzothiazines Synthesis and ActivitiesSynthesis and biological activitySynthesis and Biological Evaluation