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Small molecule targeting topoisomerase 3β for cancer therapy

Xue Zhang, Lei Wang, Qi Zhang, Song Lyu, Darong Zhu, Mengzhen Shen, Xisong Ke, Yi Qu

2021Pharmacological Research11 citationsDOI

Topics & Concepts

Cancer cellTopoisomeraseCancerCancer researchSynthetic lethalityDNA damageTopoisomerase inhibitorMutantBiologyDNAChemistryDNA repairGeneticsGeneCancer therapeutics and mechanismsBioactive Compounds and Antitumor AgentsDNA Repair Mechanisms
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