Ultrasound (US)-activated redox dyshomeostasis therapy reinforced by immunogenic cell death (ICD) through a mitochondrial targeting liposomal nanosystem
Junjie Ren, Jing Zhou, Han Liu, Xiaodan Jiao, Yang Cao, Zhigang Xu, Yuejun Kang, Peng Xue
Abstract
Taking advantage of multimodal imaging for therapy guidance, this nanoplatform may potentiate systemic tumor eradication with high certainty. Taken together, this state-of-the-art paradigm may provide useful insights for cancer management by disrupting redox homeostasis.
Topics & Concepts
GlutaminolysisReactive oxygen speciesIntracellularProgrammed cell deathRedoxMitochondrionCancer researchCellCell biologyHomeostasisChemistryCell growthApoptosisCancerMedicineCancer cellBiologyBiochemistryInternal medicineOrganic chemistryCancer, Hypoxia, and MetabolismNanoplatforms for cancer theranosticsCancer Research and Treatments