Correlation between Clinical and Wastewater SARS-CoV-2 Genomic Surveillance, Oregon, USA
Devrim Kaya, Rebecca Falender, Tyler S. Radniecki, Matthew Geniza, Paul Cieslak, Christine Kelly, Noah Lininger, Melissa Sutton
Abstract
SARS-CoV-2 variant proportions in a population can be estimated through genomic sequencing of clinical specimens or wastewater samples. We demonstrate strong pairwise correlation between statewide variant estimates in Oregon, USA, derived from both methods (correlation coefficient 0.97). Our results provide crucial evidence of the effectiveness of community-level genomic surveillance.
Topics & Concepts
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakVirologySars virusMedicineCoronavirusBiologyComputational biologyEnvironmental healthBioinformaticsInternal medicineOutbreakInfectious disease (medical specialty)DiseaseSARS-CoV-2 detection and testingSARS-CoV-2 and COVID-19 ResearchBiosensors and Analytical Detection