Quercetin Alleviates Intestinal Oxidative Damage Induced by H<sub>2</sub>O<sub>2</sub> via Modulation of GSH: In Vitro Screening and In Vivo Evaluation in a Colitis Model of Mice
Yuanyang Dong, Qihang Hou, Jiaqi Lei, Patricia G. Wolf, Hammed Ayansola, Bingkun Zhang
Abstract
-induced oxidative stress cell model based on the real-time cellular analysis system was an effective model to screen natural products to deal with intestinal oxidative damage and help accelerate the discovery of new drugs for inflammatory bowel disease (IBD).
Topics & Concepts
GCLCGlutathioneOxidative stressQuercetinChemistryReactive oxygen speciesBiochemistryPharmacologyAntioxidantBiologyEnzymeGenomics, phytochemicals, and oxidative stressSulfur Compounds in BiologyEicosanoids and Hypertension Pharmacology