SARS-CoV-2 Infection of Airway Epithelial Cells
Gwanghui Ryu, Hyun‐Woo Shin
Abstract
experiments produce chemokines and cytokines to recruit inflammatory cells to target organs. Same as other viral infections, IFN signaling is a critical pathway for host defense. Various studies are underway to confirm the pathophysiological mechanisms of SARS-CoV-2 infection. Herein, we review cellular entry, host-viral interactions, immune responses to SARS-CoV-2 in airway epithelial cells. We also discuss therapeutic options related to epithelial immune reactions to SARS-CoV-2.
Topics & Concepts
Immune systemImmunologyChemokineRespiratory epitheliumRespiratory tractAirwayMedicineBiologyCoronavirusViral entryVirologyEpitheliumRespiratory systemVirusViral replicationDiseasePathologyCoronavirus disease 2019 (COVID-19)Internal medicineInfectious disease (medical specialty)SurgeryRespiratory viral infections researchSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies