The antioxidant potential of peptides obtained from the spotted babylon snail (<i>Babylonia areolata</i>) in treating human colon adenocarcinoma (Caco-2) cells
Putcha Petsantad, Papassara Sangtanoo, Piroonporn Srimongkol, Tanatorn Saisavoey, Onrapak Reamtong, Ninnaj Chaitanawisuti, Aphichart Karnchanatat
Abstract
sub-fraction was able to prevent hydroxyl radicals from causing DNA damage by conducting tests which involved the pKS, pUC19, and pBR322 plasmids using the Fenton reaction. In addition, cellular antioxidant activity was demonstrated by two synthetic peptides toward the human adenocarcinoma colon (Caco-2) cell line, with the potency of the activity dependent upon the peptide concentration.
Topics & Concepts
ChemistryAntioxidantABTSDPPHBiochemistryHydrolysatePepsinPeptideTrypsinDigestion (alchemy)ChromatographyEnzymeHydrolysisProtein Hydrolysis and Bioactive PeptidesInsect Utilization and EffectsAquaculture Nutrition and Growth