Indole-Containing Metal Complexes and Their Medicinal Applications
Zahra Kazemi, Hadi Amiri Rudbari, Nakisa Moini, Fariborz Momenbeik, Federica Carnamucio, Nicola Micale
Abstract
Indole is an important element of many natural and synthetic molecules with significant biological activity. Nonetheless, the co-presence of transitional metals in organic scaffold may represent an important factor in the development of effective medicinal agents. This review covers some of the latest and most relevant achievements in the biological and pharmacological activity of important indole-containing metal complexes in the area of drug discovery.
Topics & Concepts
Indole testDrug discoveryBiological activityChemistryNanotechnologyCombinatorial chemistryMaterials scienceStereochemistryBiochemistryIn vitroClick Chemistry and ApplicationsSynthesis and biological activityComputational Drug Discovery Methods