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Chloroquine or hydroxychloroquine for prevention and treatment of COVID-19

Bhagteshwar Singh, Hannah Ryan, Tamara Kredo, Marty Chaplin, Tom Fletcher

2020Cochrane Database of Systematic Reviews96 citationsDOIOpen Access PDF

Abstract

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows: To evaluate the effects of chloroquine (CQ) and hydroxychloroquine (HCQ) as: 1. an antiviral treatment on death and time to clearance of the virus from clinical samples and recovery in people with COVID‐19; 2. a prophylactic treatment on prevention of COVID‐19 in people at risk of SARS‐CoV‐2 exposure; 3. a prophylactic treatment on prevention of COVID‐19 in people who have been exposed to SARS‐CoV‐2.

Topics & Concepts

HydroxychloroquineChloroquineMedicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)2019-20 coronavirus outbreakVirologyIntensive care medicineInternal medicineImmunologyMalariaOutbreakDiseaseInfectious disease (medical specialty)COVID-19 Clinical Research StudiesLong-Term Effects of COVID-19Vitamin C and Antioxidants Research
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