EGFR-targeted ionizable lipid nanoparticles enhance in vivo mRNA delivery to the placenta
Hannah C. Geisler, Aditi A. Ghalsasi, Hannah C Safford, Kelsey L Swingle, Ajay S. Thatte, Alvin J Mukalel, Ningqiang Gong, Alex G. Hamilton, Emily L Han, Benjamin E Nachod, Marshall S. Padilla, Michael J Mitchell
Topics & Concepts
EndocytosisIn vivoPlacentaAntibodyReceptorChemistryTropismGene deliveryCell biologyCancer researchImmunologyFetusMedicineBiologyTransfectionPregnancyBiochemistryVirusGeneGeneticsBiotechnologyRNA Interference and Gene DeliveryPregnancy and preeclampsia studiesNanoparticle-Based Drug Delivery