Oral health and atherosclerotic cardiovascular disease: A review
Eugenia Gianos, Elizabeth A. Jackson, Astha Tejpal, Karen Aspry, James H. O’Keefe, Monica Aggarwal, Ankur Jain, Dipti Itchhaporia, Kim A. Williams, Travis Batts, Kathleen Allen, Clark Yarber, Robert J. Ostfeld, Michael Miller, Koushik Reddy, Andrew M. Freeman, Kenneth E. Fleisher
Abstract
Periodontal disease (PD) is common in the US and globally. Evidence suggests that poor oral health is associated with atherosclerotic cardiovascular disease (ASCVD); however, this relationship has not been a major focus in clinical cardiology. This manuscript will review the growing evidence linking PD to ASCVD, including pathophysiologic mechanisms and coexistent risk factors. Public health considerations with a focus on disparities, social determinants, preventive strategies, and a call to action to reduce the burden of coincident ASCVD and PD are also reviewed.