N6-methyladenosine reader protein IGF2BP1 suppresses CD8 + T cells-mediated tumor cytotoxicity and apoptosis in colon cancer
Yao Peng, Zhili Zhang, Gong‐Li Yang, Zhongming Dai, Xunchao Cai, Zhenyu Liu, Qian Yun, Long Xu
Topics & Concepts
Immune systemCytotoxicityColorectal cancerCancer researchCytotoxic T cellImmune checkpointApoptosisCD8ImmunotherapyBiologyCancer immunotherapyDownregulation and upregulationCancerImmunologyBiochemistryIn vitroGeneticsGeneRNA modifications and cancerCancer-related molecular mechanisms researchCancer Immunotherapy and Biomarkers