Bacterial Concentrations and Water Turbulence Influence the Importance of Conjugation Versus Phage-Mediated Antibiotic Resistance Gene Transfer in Suspended Growth Systems
Ruonan Sun, Pingfeng Yu, Pengxiao Zuo, Pedro J. J. Alvarez
Abstract
values corroborate that the importance of phage delivery relative to conjugation increases under either quiescent or turbulent conditions. This finding challenges the prevailing view that conjugation is the dominant ARG transfer mechanism and underscores the need to consider and mitigate potential ARG dissemination via transduction.
Topics & Concepts
Escherichia coliLysogenic cycleBacterial conjugationTransduction (biophysics)MicrobiologyChemistryBacteriophagePlasmidBiologyHorizontal gene transferGeneMolecular biologyBiophysicsBiochemistryGenomeBacteriophages and microbial interactionsPharmaceutical and Antibiotic Environmental ImpactsFecal contamination and water quality