Immunity and autoantibodies of a mouse strain with autistic-like behavior
Mohammad Nizam Uddin, Yunyi Yao, Tapan Kumar Mondal, Rosemary Matala, Kevin Manley, Qishan Lin, David A. Lawrence
Abstract
) ratio, which increases gene expression. Identification of gene expression and immune activities of BTBR mice may aid understanding of mechanisms associated with autism since neuroimmune network interactions have been posited and induction of autoantibodies may drive the neuroinflammation associated with autism.
Topics & Concepts
AutoantibodyImmune systemAntigenImmunologyAntibodyBiologyAutism Spectrum Disorder ResearchGenetics and Neurodevelopmental DisordersImmunodeficiency and Autoimmune Disorders