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Discovery of a new class of valosine containing protein (VCP/P97) inhibitors for the treatment of colorectal cancer

Xueyuan Wang, Tiantian Wen, Hang Miao, Wenjiao Hu, Meng Lei, Yongqiang Zhu

2022Bioorganic & Medicinal Chemistry11 citationsDOIOpen Access PDF

Topics & Concepts

Colorectal cancerChemistryIn vivoCancerEnzymeCell cultureCancer researchIC50UbiquitinCell growthBiochemistryIn vitroPharmacologyBiologyGeneInternal medicineMedicineGeneticsBiotechnologyEndoplasmic Reticulum Stress and DiseaseUbiquitin and proteasome pathwaysAutophagy in Disease and Therapy
Discovery of a new class of valosine containing protein (VCP/P97) inhibitors for the treatment of colorectal cancer | Litcius