Anticancer potential of Solanaceae plants: A review
Preety Rohilla, Heena Jain, Ashmita Chhikara, L. B. Singh, Pushpa Dahiya
Abstract
Cancer with a mortality rate bordering on cardiac diseases is a multifaceted health issue that medical science is facing today. Despite various therapies available, its management is still a burning issue due to the side effects of most of the drugs used in its treatment. Plant products have always been favorable in health care management due to their effectiveness, ease of availability, and safety. The present review makes an effort to summarize the research advancements in the anti-cancer domain of Solanaceae family. Research carried out during the last ten years (2011–2020) has been briefed after reading about 320 articles published in different data sources like Google scholar, Wiley online library, Web of Science, Semantic Scholar, Scopus, and Pub Med. Altogether 213 article data have been cited, and comprehensive information of 18 utmost potential anti-cancerous plants of the family has complied. About 63 anti-cancerous compounds have been isolated from these eighteen plants. A total of 32 plant-specific anti-cancerous compounds have been tabulated along with their chemical structure and study design. The mechanism of action of specific compounds that might provoke the researcher's watchfulness for further detailed studies is also proposed. This review will come up with the perception of the role of Solanaceae family in cancer research and point out the lacuna in the ongoing knowledge and will contribute to hereafter research.