Rational Design, Pharmacomodulation, and Synthesis of [<sup>68</sup>Ga]Ga-Alb-FAPtp-01, a Selective Tumor-Associated Fibroblast Activation Protein Tracer for PET Imaging of Glioma
Jiajia Lin, Chia-Pao Chuang, Jiayu Lin, Feng‐Ting Huang, Chiun‐Wei Huang
Abstract
, permitting a precise definition of its roles in tumors of different stages and yielding insights regarding FAP-targeted radiotherapeutic strategies at the molecular level.
Topics & Concepts
Fibroblast activation protein, alphaPositron emission tomographyIn vivoGliomaStandardized uptake valueNuclear medicineMedicineBiomarkerCancer researchCancerChemistryInternal medicineBiologyBiochemistryBiotechnologyPeptidase Inhibition and AnalysisCardiac Structural Anomalies and RepairNeuropeptides and Animal Physiology